Article

A Thermo-responsive collapse system for controlling heterogeneous cell localization, ratio and interaction for three-dimensional solid tumor modeling

2024-12-26

Abstract excerpt

Cancer immunotherapy using engineered cytotoxic effector cells has demonstrated significant potential. The limited spatial complexity of existing in vitro models, however, poses a challenge to mechanistic studies attempting to approve existing approaches of effector cell-mediated cytotoxicity within a three-dimensional, solid tumor-like environment. To gain additional experimental control, we developed an approac...

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Literature Corpus work: 074889bd-c971-5ae4-9dec-4cc9282f1892
DOI: 10.1101/2024.12.26.630018

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