Planar arrangement of eukaryotic cells in merged hydrogels combines the advantages of 3-D and 2-D cultures.

Abstract excerpt

We report an unordered 2-D array of eukaryotic cells completely embedded in a 3-D matrix. Every cell is located at the same distance from the gel surface, which ensures uniformity of growth conditions and ease of observation characteristic of a 2-D culture. Each cell is firmly immobilized, and each has a unique address in the array. The cells can be rapidly screened, individually monitored during extended time...

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