Article

Differential expression of the nuclear-encoded mitochondrial transcriptome in pediatric septic shock

2014-01-01

Abstract excerpt

Increasing evidence supports a role for mitochondrial dysfunction in organ injury and immune dysregulation in sepsis. Although differential expression of mitochondrial genes in blood cells has been reported for several diseases in which bioenergetic failure is a postulated mechanism, there are no data about the blood cell mitochondrial transcriptome in pediatric sepsis. We conducted a focused analysis using a mult...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0748601d-5a1d-595a-8bc8-730758940adf
DOI: 10.1186/preaccept-2292040841290621

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Differential expression of the nuclear-encoded mitochondrial transcriptome in pediatric septic shockDOI 10.1186/preaccept-2292040841290621Read

Differential expression of the nuclear-encoded mitochondrial transcriptome in pediatric septic shockSemantic proximity Read

Differential gene expression analysis reveals novel genes and pathways in pediatric septic shock patientsSemantic proximity Read

Differential gene expression analysis reveals novel genes and pathways in pediatric septic shock patientsSemantic proximity Read

Identification of sepsis-associated mitochondrial genes through RNA and single-cell sequencing approachesSemantic proximity Read

Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcomeSemantic proximity Read

Whole blood transcriptomics identifies subclasses of pediatric septic shockSemantic proximity Read

Whole Blood Transcriptomics Identifies Subclasses of Pediatric Septic ShockSemantic proximity Read

Validating the genomic signature of pediatric septic shockSemantic proximity Read

Derivation, Validation, and Clinical Relevance of a Pediatric Sepsis Phenotype With Persistent Hypoxemia, Encephalopathy, and Shock.Semantic proximity Read

Leukocyte subset-derived genomewide expression profiles in pediatric septic shock*Semantic proximity Read

Applying Transcriptomics for an Enhanced Clinical Research Framework, Implications for an Improved Research Strategy based on an Omics Approach: A Scoping ReviewSemantic proximity Read

Mitochondrial-related genome-wide Mendelian randomization identifies putatively causal genes in the pathogenesis of sepsisSemantic proximity Read