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Article

Whole blood transcriptomics identifies subclasses of pediatric septic shock

8 Dec 2023

Abstract excerpt

BACKGROUND: Sepsis is a highly heterogeneous syndrome, which has hindered the development of effective therapies. This has prompted investigators to develop a precision medicine approach aimed at identifying biologically homogenous subgroups of patients with septic shock and critical illnesses. Transcriptomic analysis can identify subclasses derived from differences in underlying pathophysiological processes that...

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PMID: 38066613
DOI: 10.1186/s13054-023-04689-y

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