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Leukocyte subset-derived genomewide expression profiles in pediatric septic shock*

1 Dec 2009

Abstract excerpt

OBJECTIVE: To directly assess whether genomewide expression profiles derived from leukocyte subsets are comparable to that of whole blood as measured by enrichment for genes corresponding to metabolic and signaling pathways. DESIGN: Prospective observational study involving microarray-based bioinformatics based on RNA individually derived from whole blood, neutrophils, monocytes, and lymphocytes, respectively....

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PMID: 20009785
DOI: 10.1097/pcc.0b013e3181c519b4

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