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Identification of sepsis-associated mitochondrial genes through RNA and single-cell sequencing approaches

3 May 2024

Abstract excerpt

BACKGROUND: Sepsis ranks among the most formidable clinical challenges, characterized by exorbitant treatment costs and substantial demands on healthcare resources. Mitochondrial dysfunction emerges as a pivotal risk factor in the pathogenesis of sepsis, underscoring the imperative to identify mitochondrial-related biomarkers. Such biomarkers are crucial for enhancing the accuracy of sepsis diagnostics and...

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PMID: 38702721
DOI: 10.1186/s12920-024-01891-x

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