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Brain DNA methylomic analysis of frontotemporal lobar degeneration reveals <i>OTUD4</i> in shared dysregulated signatures across pathological subtypes

2022-10-22

Abstract excerpt

<h4>ABSTRACT</h4> Frontotemporal lobar degeneration (FTLD) is an umbrella term describing the neuropathology of a clinically, genetically and pathologically heterogeneous group of diseases, including frontotemporal dementia (FTD) and progressive supranuclear palsy (PSP). Among the major FTLD pathological subgroups, FTLD with TDP-43 positive inclusions (FTLD-TDP) and FTLD with tau positive inclusions (FTLD-tau) ar...

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Literature Corpus work
073ea937-e3f6-5d41-996e-fc9e24ae5939
DOI
10.1101/2022.10.21.513088
Open publication

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Brain DNA methylomic analysis of frontotemporal lobar degeneration reveals <i>OTUD4</i> in shared dysregulated signatures across pathological subtypesDOI 10.1101/2022.10.21.513088
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