Article
A multi-omics dataset for the analysis of frontotemporal dementia genetic subtypes.
Scientific data - 1 Dec 2023
Menden Kevin, Francescatto Margherita, Nyima Tenzin, Blauwendraat Cornelis, Dhingra Ashutosh, Castillo-Lizardo Melissa, Fernandes Noémia, Kaurani Lalit, Kronenberg-Versteeg Deborah, Atasu Burcu, Sadikoglou Eldem, Borroni Barbara, Rodriguez-Nieto Salvador, Simon-Sanchez Javier, Fischer Andre, Craig David Wesley, Neumann Manuela, Bonn Stefan, Rizzu Patrizia, Heutink Peter
Abstract excerpt
Understanding the molecular mechanisms underlying frontotemporal dementia (FTD) is essential for the development of successful therapies. Systematic studies on human post-mortem brain tissue of patients with genetic subtypes of FTD are currently lacking. The Risk and Modyfing Factors of Frontotemporal Dementia (RiMod-FTD) consortium therefore has generated a multi-omics dataset for genetic subtypes of FTD to...
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