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Targeting endothelial FOXO1 protects diabetic β-cells and improves wound healing

2023-12-05

Abstract excerpt

The forkhead box O1 (FOXO1) transcription factor plays critical roles in regulating not only metabolic activity but also angiogenesis in the vascular endothelium 1–4 . Our previous studies show that epsin endocytic adaptors can regulate both angiogenesis and lymphangiogenesis 5–7 . Endothelial cells (ECs) lining the inside of blood vessels are continuously exposed to circulating insulin and insulin-like growth f...

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Literature Corpus work
06fe591f-f10b-5cd0-aeef-8274bc0400b2
DOI
10.1101/2023.12.04.569948
Open publication

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Targeting endothelial FOXO1 protects diabetic β-cells and improves wound healingDOI 10.1101/2023.12.04.569948
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