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Article

Structure and Function of Sodium Channel Nav1.3 in Neurological Disorders.

Cellular and molecular neurobiology - 1 Mar 2023

Liao Sheng, Liu Tao, Yang Ruozhu, Tan Weitong, Gu Jiaqi, Deng Meichun

Abstract excerpt

Nav1.3, encoded by the SCN3A gene, is a voltage-gated sodium channel on the cell membrane. It is expressed abundantly in the fetal brain but little in the normal adult brain. It is involved in the generation and conduction of action potentials in excitable cells. Nav1.3 plays an important role in many neurological diseases. The aim of this review is to summarize new findings about Nav1.3 in the field of...

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PMID: 35332400
DOI: 10.1007/s10571-022-01211-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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