Article
Global adaptation to a lipid environment triggers the dormancy-related phenotype of Mycobacterium tuberculosis.
mBio - 20 May 2014
Rodríguez Juan G, Hernández Adriana C, Helguera-Repetto Cecilia, Aguilar Ayala Diana, Guadarrama-Medina Rosalina, Anzóla Juan M, Bustos Jose R, Zambrano María M, González-Y-Merchand Jorge, García María J, Del Portillo Patricia
Abstract excerpt
UNLABELLED: Strong evidence supports the idea that fatty acids rather than carbohydrates are the main energy source of Mycobacterium tuberculosis during infection and latency. Despite that important role, a complete scenario of the bacterium's metabolism when lipids are the main energy source is still lacking. Here we report the development of an in vitro model to analyze adaptation of M. tuberculosis during...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.