Article

Inferring a directed acyclic graph of phenotypes from GWAS summary statistics

2023-02-11

Abstract excerpt

<h4> S ummary </h4> Estimating phenotype networks is a growing field in computational biology. It deepens the understanding of disease etiology and is useful in many applications. In this study, we present a method that constructs a phenotype network by assuming a Gaussian linear structure model embedding a directed acyclic graph (DAG). We utilize genetic variants as instrumental variables and show how our meth...

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Literature Corpus work: 585b5c7e-9dc2-5d49-bb52-fc00a8beb5af
DOI: 10.1101/2023.02.10.528092

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