Article

Signatures of selection at drug resistance loci in <i>Mycobacterium tuberculosis</i>

2017-08-07

Abstract excerpt

Tuberculosis (TB) is the leading cause of death by an infectious disease, and global TB control efforts are increasingly threatened by drug resistance in Mycobacterium tuberculosis (M. tb). Unlike most bacteria, where lateral gene transfer is an important mechanism of resistance acquisition, resistant M. tb arises solely by de novo chromosomal mutation. Using whole genome sequencing data from two natural popula...

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Literature Corpus work: 994fb918-e1a8-5c39-b47c-5546e1ba2a00
DOI: 10.1101/173229

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