Article

Golgi-localised Guanylate-binding protein 5 enhances glycolysis in macrophages

2026-02-18

Abstract excerpt

<h4>ABSTRACT</h4> Guanylate-binding proteins (GBPs) are part of a family of large interferon gamma (IFNψ)-inducible GTPases, with ascribed roles in infection control and induction of programmed cell death. While pathogen-specific functions of GBPs have been studied in detail, their broader regulation of frontline immune defences remain unexplored. Here, we analysed the global contribution of human GBP1-5 to cellu...

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Literature Corpus work: 06572c25-0331-5aa7-bd06-63d8cf2321db
DOI: 10.64898/2026.02.17.706357

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