Article

The autism-associated gene SYNGAP1 regulates human cortical neurogenesis

2022-05-10

Abstract excerpt

Autism spectrum disorder (ASD) is a genetically heterogeneous disorder linked with rare, inherited and de novo mutations occurring in two main functional gene categories: gene expression regulation and synaptic function 1 . Accumulating evidence points to dysregulation in cortical neurogenesis as a convergent mechanism in ASD pathophysiology 2-8 . While asynchronous development has been identified as a shared f...

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Literature Corpus work: 05ec3129-ab06-568f-b66e-c03a9d57168f
DOI: 10.1101/2022.05.10.491244

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