Article

The autism-associated gene SYNGAP1 regulates human cortical neurogenesis

2022-05-10

Abstract excerpt

<title>Abstract</title> <p>Autism spectrum disorder (ASD) is a genetically heterogeneous disorder linked with rare, inherited and de novo mutations occurring in two main functional gene categories: gene expression regulation and synaptic function1. Accumulating evidence points to dysregulation in cortical neurogenesis as a convergent mechanism in ASD pathophysiology. While asynchronous development has been identi...

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Literature Corpus work: c7b46a31-212b-5298-bc0c-d413485df876
DOI: 10.21203/rs.3.rs-1610145/v1

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