Article

Contributions of circadian clock genes to cell survival in fibroblast models of lithium-responsive bipolar disorder.

2022-09-07

Abstract excerpt

<title>Abstract</title> <p>Bipolar disorder (BD) is characterized by mood episodes, disrupted circadian rhythms and gray matter reduction in the brain. Lithium is an effective pharmacotherapy for BD, but not all patients respond to treatment. Lithium has neuroprotective properties and beneficial effects on circadian rhythms that may distinguish lithium responders (Li-R) from non-responders (Li-NR). The circadian...

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Literature Corpus work: 05d68478-7173-5162-8a3e-1211787206e1
DOI: 10.21203/rs.3.rs-2003560/v1

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