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Article

Lithium response in bipolar disorders and core clock genes expression

18 Jan 2017

Abstract excerpt

OBJECTIVES: We examine whether the lithium response is associated with changes in the expression of core clock genes. METHODS: The effect of a therapeutic concentration of lithium (1 mM) on the expression levels of 17 circadian genes was examined in lymphoblastoid cell lines (LCLs) derived from two well-characterized groups of bipolar disorder patients, defined as lithium non-responders (NR, n = 20) or excellent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28095742
DOI: 10.1080/15622975.2017.1282174

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