Article

Characterisation of the phenotype and function of drug-responsive T-cells in patients with drug-induced liver injury

2021-01-01

Abstract excerpt

Hypersensitivity reactions to drugs are an important cause of patient morbidity and mortality. One of the most difficult problems for the pharmaceutical industry is prediction of drugs with liver liabilities during the early stages of development. There is an incomplete understanding of the pathways of drug-specific immune cell activation and how the induced immune responses result in clinical manifestations in th...

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Literature Corpus work: 059b5891-73c7-5afe-a15a-d2297ab39bd4
DOI: 10.17638/03148287

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