Article

Analysis of drug-protein adducts and their role in drug hypersensitivity

2018-01-01

Abstract excerpt

Idiosyncratic drug reactions are extremely severe and are not attributed to the normal pharmacology of a drug. Elucidating their toxicological mechanisms have been challenging. In recent years, idiosyncratic drug-induced liver injury (iDILI) has been linked with the immune system proposing that tissue damage may be mediated by the cytotoxicity of T-cells. Furthermore, several associations have been found with iDIL...

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Literature Corpus work: af857583-05d1-5df6-b3ab-58ac3f71e544
DOI: 10.17638/03033177

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