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Neutrophil progenitor cell therapy rescues host defense against <i>Staphylococcus aureus</i> in murine chronic granulomatous disease

2025-03-30

Abstract excerpt

Despite advances in engineered adaptive immune cell therapies, current options for innate immune cell therapies are sparse. In this work, we demonstrate the utility of a neutrophil progenitor-based cell therapy. Murine conditionally-immortalized neutrophil progenitors (NPs) overcome the hurdles of alternative cell therapies by engrafting in the unconditioned host and substantially contributing to the host neutroph...

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Identifiers and source

Literature Corpus work
056c0014-14f6-51e2-9144-02ce554c1ce0
DOI
10.1101/2025.03.26.645550
Open publication

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Neutrophil progenitor cell therapy rescues host defense against <i>Staphylococcus aureus</i> in murine chronic granulomatous diseaseDOI 10.1101/2025.03.26.645550
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