Article

Sequence neighborhoods enable reliable prediction of pathogenic mutations in cancer genomes

2021-02-11

Abstract excerpt

Identifying cancer-causing mutations from sequenced cancer genomes hold much promise for targeted therapy and precision medicine. “Driver” mutations are primarily responsible for cancer progression, while “passengers” are functionally neutral. Although several computational approaches have been developed for distinguishing between driver and passenger mutations, very few have concentrated on utilizing the raw nucl...

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Literature Corpus work: e3156ee5-29b3-54b4-8107-3153ef5dc5f0
DOI: 10.1101/2021.02.09.430460

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