Article

CHASMplus reveals the scope of somatic missense mutations driving human cancers

2018-05-02

Abstract excerpt

<h4>Summary</h4> Large-scale cancer sequencing studies of patient cohorts have statistically implicated many genes driving cancer growth and progression, and their identification has yielded substantial translational impact. However, a remaining challenge is to increase the resolution of driver prediction from the gene level to the mutation level, because mutation-level predictions are more closely aligned with t...

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Literature Corpus work: 134987e7-95d8-5430-b14e-90f902782b2b
DOI: 10.1101/313296

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