Article

BDNF augmentation reverses cranial radiation therapy-induced cognitive decline and neurodegenerative consequences

2024-10-10

Abstract excerpt

<title>Abstract</title> <p>Cranial radiation therapy (RT) for brain cancers is often associated with the development of radiation-induced cognitive dysfunction (RICD). RICD significantly impacts the quality of life for cancer survivors, highlighting an unmet medical need. Previous human studies revealed a marked reduction in plasma brain-derived neurotrophic factor (BDNF) post-chronic chemotherapy, linking this d...

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Literature Corpus work: 055f5258-589a-5901-b45c-79d285002952
DOI: 10.21203/rs.3.rs-5014456/v1

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