Article
Curly tail: a 50-year history of the mouse spina bifida model.
Anatomy and embryology - 1 Apr 2001
van Straaten H W, Copp A J
Abstract excerpt
This paper reviews 50 years of progress towards understanding the aetiology and pathogenesis of neural tube defects (NTD) in the curly tail (ct) mutant mouse. More than 45 papers have been published on various aspects of curly tail with the result that it is now the best understood mouse model of NTD pathogenesis. The failure of closure of the spinal neural tube, which leads to spina bifida in this mouse, has...
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