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Article

Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects.

Birth defects research. Part A, Clinical and molecular teratology - 1 Mar 2007

Harris Muriel J, Juriloff Diana M

Abstract excerpt

BACKGROUND: The number of mouse mutants and strains with neural tube closure defects (NTDs) now exceeds 190, including 155 involving known genes, 33 with unidentified genes, and eight "multifactorial" strains. METHODS: The emerging patterns of mouse NTDs are considered in relation to the unknown genetics of the common human NTDs, anencephaly, and spina bifida aperta. RESULTS: Of the 150 mouse mutants that survive...

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PMID: 17177317
DOI: 10.1002/bdra.20333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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