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Neural tube defects—disorders of neurulation and related embryonic processes

29 May 2012

Abstract excerpt

Neural tube defects (NTDs) are severe congenital malformations affecting 1 in every 1000 pregnancies. 'Open' NTDs result from failure of primary neurulation as seen in anencephaly, myelomeningocele (open spina bifida), and craniorachischisis. Degeneration of the persistently open neural tube in utero leads to loss of neurological function below the lesion level. 'Closed' NTDs are skin-covered disorders of spinal...

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Share to Assisted Reproductive Technology and Twin Pregnancy
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PMID: 24009034
DOI: 10.1002/wdev.71

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