Article
Spina Bifida: Pathogenesis, Mechanisms, and Genes in Mice and Humans
1 Jan 2017
Abstract excerpt
Spina bifida is among the phenotypes of the larger condition known as neural tube defects (NTDs). It is the most common central nervous system malformation compatible with life and the second leading cause of birth defects after congenital heart defects. In this review paper, we define spina bifida and discuss the phenotypes seen in humans as described by both surgeons and embryologists in order to compare and...
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