Article
[Pathogenesis and genetics of neural tube defects].
Ginekologia polska - 1 Dec 2007
Witczak Monika, Ferenc Tomasz, Wilczyński Jan
Abstract excerpt
After congenital heart defects neural tube defects (NTDs) is the second most prevalent congenital malformation among birth defects. The average rate of isolated NTDs is 1.4-2.0 per 1000 live births worldwide. The etiology of isolated (nonsyndromic) NTDs is believed to be the result of a combination of genetic predisposition and environmental factors. Over 80 genes believed to be engaged in the neurulations have...
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