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Article

Intranasal CRISPR- lipid nanoparticles targeting MAPK9 reduce neuroinflammation after traumatic brain injury

2026-05-14

Abstract excerpt

<title>Abstract</title> <p> Traumatic brain injury (TBI) triggers a sustained neuroinflammatory response driven by activated microglia, which contributes to secondary injury and long-term neurological dysfunction. Therapeutic reprogramming of microglial activation from a pro-inflammatory (M1-like) to a reparative (M2-like) phenotype represents a promising strategy; however, the lack of cell-specific targeting wi...

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Literature Corpus work
052b98b8-f492-5b17-8a85-dedbacdbb00c
DOI
10.21203/rs.3.rs-9521461/v1
Open publication

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Intranasal CRISPR- lipid nanoparticles targeting MAPK9 reduce neuroinflammation after traumatic brain injuryDOI 10.21203/rs.3.rs-9521461/v1
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