Article

Strategies for addressing pseudoreplication in multi-patient scRNA-seq data

2024-06-17

Abstract excerpt

The rapidly evolving field of single-cell transcriptomics has provided a powerful means for understanding cellular heterogeneity. Large-scale studies with multiple biological samples hold promise for discovering differentially expressed biomarkers with a higher level of confidence through a better characterization of the target population. However, the hierarchical nature of these experiments introduces a signific...

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Literature Corpus work: 05109dc6-e149-5dc7-bd72-d0e7cc69f501
DOI: 10.1101/2024.06.15.599144

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