Article

Harmonizing Heterogeneous Single-cell Gene Expression Data with Individual-level Covariate Information

2025-04-20

Abstract excerpt

<h4>Motivation</h4> The growing availability of single-cell RNA sequencing (scRNA-seq) data highlights the necessity for robust integration methods to uncover both shared and unique cellular features across samples. These datasets often exhibit technical variations and biological differences, complicating integrative analyses. While numerous integration methods have been proposed, many fail to account for individ...

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Literature Corpus work: 1ce8d8fe-f35e-5e99-9d28-6a21a9ca2d6f
DOI: 10.1101/2025.04.15.649009

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