Article

RegVelo: gene-regulatory-informed dynamics of single cells

2024-12-11

Abstract excerpt

RNA velocity has emerged as a popular approach for modeling cellular change along the phenotypic landscape but routinely omits regulatory interactions between genes. Conversely, methods that infer gene regulatory networks (GRNs) do not consider the dynamically changing nature of biological systems. To integrate these two currently disconnected fields, we present RegVelo, an end-to-end dynamic, interpretable, and a...

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Literature Corpus work: c1ade7ae-2ebc-576f-99cd-c1138a37470b
DOI: 10.1101/2024.12.11.627935

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