Article

Investigating the antibody-independent functions of B lymphocytes

2019-01-01

Abstract excerpt

B cells are critical for the generation of antibody, but there is increasing evidence that they have a broader functional remit: For example, innate B1a cells are a critical source of granulocyte macrophage colony-stimulating factor (GM-CSF) during Gram-negative sepsis, inducing neutrophil expansion and mobilisation to limit bacteraemia. B cells can also regulate immune responses via the production of cytokines su...

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Literature Corpus work: 0508e6b2-5443-5fde-b5b7-dbb8a7b804e7
DOI: 10.17863/cam.40748

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