Article

Human IL-10-producing B cells have diverse states induced from multiple B cell subsets

2021-09-02

Abstract excerpt

Regulatory B cells (Bregs) can suppress immune responses through the secretion of IL-10 and other anti-inflammatory cytokines. This immunomodulatory capacity holds therapeutic potential, yet a definitional immunophenotype for enumeration and prospective isolation of B cells capable of IL-10 production remains elusive. We therefore applied mass cytometry to simultaneously quantify cytokine production and immunophen...

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Literature Corpus work: b8e14b38-6edb-5701-bc18-a033a4b78766
DOI: 10.1101/2021.09.01.458645

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