The Role of Regulatory B cells in Kidney Diseases.

doi:10.3389/fimmu.2021.683926

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Article

The Role of Regulatory B cells in Kidney Diseases.

Frontiers in immunology - 1 Jan 2021

Long Wang, Zhang Hedong, Yuan Wenjia, Lan Gongbin, Lin Zhi, Peng Longkai, Dai Helong

Abstract excerpt

B cells, commonly regarded as proinflammatory antibody-producing cells, are detrimental to individuals with autoimmune diseases. However, in recent years, several studies have shown that regulatory B (Breg) cells, an immunosuppressive subset of B cells, may exert protective effects against autoimmune diseases by secretion of inhibitory cytokines such as IL-10. In practice, Breg cells are identified by their...

Topics

B-Lymphocytes, Regulatory
Cytokines
Humans
Kidney Diseases
Phenotype

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Identifiers

PMID: 34108975
DOI: 10.3389/fimmu.2021.683926
PMCID: PMC8183681

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