Article

Investigation of novel therapeutic strategies in B cell and antibody mediated disease

2019-01-01

Abstract excerpt

Terminally differentiated B cells are responsible for antibody generation, a key component of adaptive immunity. IgG antibodies play an important role in defence against infection but can be pathogenic in some autoimmune diseases and in solid organ transplantation. In addition to antibody generation, there is increasing interest in the antibody-independent functions of B cells, including their ability to regulate...

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Literature Corpus work: 94fbca07-5c58-5e42-a0ff-418b4786d0ea
DOI: 10.17863/cam.33536

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