Article
MicroRNA biogenesis and variability.
Biomolecular concepts - 1 Aug 2013
García-López Jesús, Brieño-Enríquez Miguel A, Del Mazo Jesús
Abstract excerpt
MicroRNAs (miRNAs) are cell-endogenous small noncoding RNAs that, through RNA interference, are involved in the posttranscriptional regulation of mRNAs. The biogenesis and function of miRNAs entail multiple elements with different alternative pathways. These confer a high versatility of regulation and a high variability to generate different miRNAs and hence possess a broad potential to regulate gene expression....
Topics
- Animals
- Gene Expression Regulation
- Genetic Variation
- Humans
- MicroRNAs
- Polymorphism, Single Nucleotide
- RNA Editing
- RNA Interference
- RNA Isoforms
- RNA, Messenger