Article

Nonmonotone invasion landscape by engineered control of metastasis activator levels

2022-03-11

Abstract excerpt

<title>Abstract</title> <p>A major pharmacological goal is targeting oncogenic transcription factors, by the assumption that lowering disease-promoting protein levels is generally beneficial. For example, inhibiting metastasis activator BACH1 is proposed to decrease metastasis in human cancers. Testing such assumptions requires measuring disease phenotypes while precisely adjusting disease-promoting protein level...

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Literature Corpus work: 04cc8c2e-b58b-5d26-8b41-63e7ee9cc6b3
DOI: 10.21203/rs.3.rs-1397347/v1

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