Article

Spatial Engineering: The Design Era of Oncology

2025-11-24

Abstract excerpt

Precision oncology has progressed through three eras: the genomic era, which identified mutations and molecular circuits; the archetype era, which revealed recurring tumor ecosystems; and now the emerging engineering era, enabled by AI and spatial modeling, which allows the rational reprogramming of tissue architecture. We define Spatial Engineering as a framework that integrates cellular composition, topology, ph...

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Literature Corpus work: 1f02cb01-40f0-5c79-9a8c-6abdc900f158
DOI: 10.20944/preprints202511.1782.v1

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