Article

Transcriptome Sequencing Reveals Sex Differences in Human Meniscal Cell Response to Estrogen Based on Dosing Kinetics

2020-04-29

Abstract excerpt

<h4>ABSTRACT</h4> Osteoarthritis is a disease marked by progressive and irreversible hyaline cartilage and fibrocartilage breakdown that affects the lives of millions of patients worldwide. Female sex and menopause are both risk factors for knee osteoarthritis, indicating that estrogen could play a role in this disease. In this study, RNA sequencing was used to determine the effects of estrogen treatment on human...

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Literature Corpus work: 869e4c58-ca84-532e-8c0a-d09dac88b40b
DOI: 10.1101/2020.04.27.064451

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