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A new human in vitro model of cytotypic and testosterone-producing organoids derived from testicular tissue of transgender women

1 Jan 2025

Abstract excerpt

STUDY QUESTION: Can testicular tissue from trans women (trans tissue) be used to create human testicular organoids? SUMMARY ANSWER: Testosterone-producing and cytotypic human testicular organoids with bicompartmental architecture can be successfully generated from trans tissue. WHAT IS KNOWN ALREADY: Testicular organoids are a promising tool for studying testicular function and the effects of toxicants. Immature...

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Pluripotent Stem Cells Research
Sperm and Testicular Function
Testicular diseases and treatments

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40896146
DOI: 10.1093/hropen/hoaf043

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