Article

Bayestrat: Population Stratification Correction Using Bayesian Shrinkage Prior for Genetic Association Studies

2021-03-24

Abstract excerpt

In genetic association studies with common diseases, population stratification is a major source of confounding. Principle component regression (PCR) and linear mixed model (LMM) are two commonly used approaches to account for population stratification. Previous studies have shown that LMM can be interpreted as including all principle components (PCs) as random-effect covariates. However, including all PCs in LMM...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 04b749f6-cb2f-5b7a-95f2-6f89c241ef86
DOI: 10.1101/2021.03.23.436705

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bayestrat: Population Stratification Correction Using Bayesian Shrinkage Prior for Genetic Association StudiesDOI 10.1101/2021.03.23.436705Read

Population stratification correction using Bayesian shrinkage priors for genetic association studies.Semantic proximity Read

Bayesian LASSO for population stratification correction in rare haplotype association studies.Semantic proximity Read

Quantification of population structure using correlated SNPs by shrinkage principal components.Semantic proximity Read

Evaluation of population stratification adjustment using genome-wide or exonic variants.Semantic proximity Read

A comparison of association methods correcting for population stratification in case-control studies.Semantic proximity Read

Principal components analysis corrects for stratification in genome-wide association studies.Semantic proximity Read

Control of population stratification by correlation-selected principal components.Semantic proximity Read

Accounting for population stratification in DNA methylation studies.Semantic proximity Read

Fast and efficient correction for population stratification in multi-locus genome-wide association studies.Semantic proximity Read

A Nonparametric Regression Approach to Control for Population Stratification in Rare Variant Association Studies.Semantic proximity Read

Robust methods for population stratification in genome wide association studiesSemantic proximity Read

Bayesian Multivariate Genetic Analysis Boosts Translational InsightsSemantic proximity Read