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Article

Quantification of population structure using correlated SNPs by shrinkage principal components.

Human heredity - 1 Jan 2010

Zou Fei, Lee Seunggeun, Knowles Michael R, Wright Fred A

Abstract excerpt

BACKGROUND/AIMS: Association studies using unrelated individuals have become the most popular design for mapping complex traits. One of the major challenges of association mapping is avoiding spurious association due to population stratification. Principal component analysis (PCA) on genome-wide marker genotypes is one of the most popular population stratification control methods. It implicitly assumes that the...

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PMID: 20413978
DOI: 10.1159/000288706
PMCID: PMC2912642

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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