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Article

PAK1, PAK1Δ15, and PAK2: similarities, differences and mutual interactions

2019-03-18

Abstract excerpt

P21-activated kinases (PAK) are key effectors of the small GTPases Rac1 and Cdc42, as well as of Src family kinases. In particular, PAK1 has several well-documented roles, both kinase-dependent and kinase-independent, in cancer-related processes, such as cell proliferation, adhesion, and migration. However, PAK1 properties and functions have not been attributed to individual PAK1 isoforms: besides the full-length...

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Literature Corpus work
04609a25-b721-58cb-8516-ec25f7765d9d
DOI
10.1101/580928
Open publication

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PAK1, PAK1Δ15, and PAK2: similarities, differences and mutual interactionsDOI 10.1101/580928
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