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Article

p41-Arc subunit of human Arp2/3 complex is a p21-activated kinase-1-interacting substrate.

EMBO reports - 1 Feb 2004

Vadlamudi Ratna K, Li Feng, Barnes Christopher J, Bagheri-Yarmand Rozita, Kumar Rakesh

Abstract excerpt

The formation of new branched actin filament networks at the cell cortex of migrating cells is choreographed by the actin-related protein (Arp) 2/3 complex. Despite the fundamental role of the Arp2/3 complex in actin nucleation and branching, upstream signals that control the functions of p41-Arc, a putative regulatory component of the mammalian Arp2/3 complex, remain unidentified. Here we show that p41-Arc...

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Identifiers

PMID: 14749719
DOI: 10.1038/sj.embor.7400079
PMCID: PMC1298990

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Source receipt: pubmed, retrieved 7 Sept 2026.

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