Article

CAR-Engineered Human Hematopoietic Stem Cell Macrophages Control Solid Tumors

2026-05-28

Abstract excerpt

<h4>ABSTRACT</h4> Chimeric antigen receptor (CAR) T-cells have represented a groundbreaking advance in the control of hematological cancers. However, their efficacy in controlling solid tumors has been rather limited, highlighting the importance of new cell-based therapies strategies to curb the progression of solid cancers. Here, we generated functional macrophages from human umbilical cord blood derived CD34+ h...

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Literature Corpus work: 042d957c-3a87-565b-abe6-00c6e9c27f27
DOI: 10.64898/2026.05.27.725267

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