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Article

Manipulating macrophage polarization in cancer patients: From nanoparticles to human chimeric antigen receptor macrophages.

Biochimica et biophysica acta. Reviews on cancer - 1 Aug 2021

Santoni Matteo, Massari Francesco, Montironi Rodolfo, Battelli Nicola

Abstract excerpt

Chimeric antigen receptor (CAR) T cell treatment has provided notable results in hematological tumors. Unfortunately, this evidence has not been translated into improved outcomes in solid malignancies so far, where several reports have suggested that T cells encounter substantial difficulties in penetrating and surviving in the tumor microenvironment (TME). Thus, researchers have recently investigated other...

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Identifiers

PMID: 33932561
DOI: 10.1016/j.bbcan.2021.188547

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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