Article

A conserved Arf-GEF modulates axonal integrity through RAB-35 by altering neuron-epidermal attachment

2025-06-07

Abstract excerpt

Neurites of sensory neurons densely innervate the skin and are embedded within it. These delicate structures are exposed to acute and chronic mechanical strain and yet their integrity is maintained throughout life. Although evidence suggests a neuroprotective role for the skin, the molecular pathways involved are still poorly understood. In C. elegans , the cytoskeletal molecule UNC-70/β-spectrin functions in syn...

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Literature Corpus work: 041e0d5e-b959-539a-b271-b5bf4ce51f09
DOI: 10.1101/2025.06.03.657768

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