Article

An immune-centric exploration of BRCA1 and BRCA2 germline mutation related breast and ovarian cancers

2020-02-05

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> BRCA1/2 germline mutation related cancers are candidates for new immune therapeutic interventions. This study was a hypothesis generating exploration of genomic data collected at diagnosis for 19 patients. The prominent tumor mutation burden (TMB) in hereditary breast and ovarian cancers in this cohort was not correlated with high global immune activity in their...

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Literature Corpus work: 040745c6-f55e-527c-b1e1-1a7815f598f5
DOI: 10.21203/rs.2.14626/v4

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